Hyper IgM Syndrome Meaning
Hyper IgM Syndrome (HIGM) is a primary immunodeficiency condition where the body produces too much of IgM antibodies but not IgG, IgA, and IgE antibodies. This causes frequent infections and impaired immunity.
Causes of Hyper IgM Syndrome
- Genetic mutations in immune system signaling pathways
- X-linked Hyper IgM Syndrome (XHIGM) – The most frequent type, occurs in males
- Autosomal recessive forms – Both genders are affected but less common
- Deficiency in CD40 ligand (CD40L), which is important for normal immune response
Symptoms of Hyper IgM Syndrome in Adults
- frequent infections – Bacterial, viral, and fungal infections
- respiratory infections – Chronic pneumonia, sinusitis, bronchitis
- Chronic diarrhea – Due to gastrointestinal infections
- autoimmune disorders – Some patients develop lupus-like symptoms
- liver and blood disorders – Neutropenia, anemia, and liver damage
Life Expectancy of Hyper IgM Syndrome
- Untreated: Life expectancy is decreased substantially due to infections and organ injury
- Treated: Most patients live into adulthood, but complications depend on severity
- Bone marrow transplant is the only hope of a cure
Homeopathy Treatment of Hyper IgM Syndrome
Homeopathy may aid immune function but cannot substitute for regular treatment.
1. Thuja Occidentalis
-Improve immune function in immunocompromised patients
2 . Echinacea
-Enhance natural immunity
3 . Silicea
-Aide in chronic infections and respiratory disturbances
4 . Arsenicum Album
-Support lungs and respiratory tract
-Beneficial for long-standing respiratory infections
5. Calcarea Phosphorica
-Maintains general immune balance
Conclusion
Hyper IgM Syndrome (HIGM) is a serious immunodeficiency condition that results in recurrent infections and a shortened lifespan if left untreated. Bone marrow transplantation and immunoglobulin treatment are essential, with homeopathy as an auxiliary measure to enhance immunity.
FAQs
- What is Hyper IgM Syndrome?
HyperIgM Syndrome (HIGM) is a rare immune deficiency disorder where the immune system produces too many IgM antibodies but fails to produce IgG, IgA, and IgE antibodies, leading to recurrent infections and a weakened immune response.
- What causes Hyper IgM Syndrome?
HIGM is caused by genetic mutations affecting the immune system, primarily in the CD40 ligand (CD40L) gene. The most common type is X-linked Hyper IgM Syndrome (XHIGM), which mainly affects males.
- What are the symptoms of Hyper IgM Syndrome in adults?
- Frequent infections (pneumonia, sinusitis, bronchitis)
- Chronic diarrhea (due to gut infections)
- Liver disease and autoimmune disorders
- Blood abnormalities (anemia, neutropenia)
- What is the life expectancy for someone with Hyper IgM Syndrome?
Without treatment, life expectancy is severely reduced due to chronic infections. With immunoglobulin therapy and bone marrow transplants, some patients can live into adulthood and beyond.
To schedule an appointment or learn more about our treatment, please visit our website or give us a call +91 9595211594 Our friendly staff will be happy to assist you. If you’re searching for the best homeopathy doctor, we are here to help.
Follow us on Facebook, Twitter, and Instagram for valuable insights into the world of homeopathy and holistic health.
Facebook – https://www.facebook.com/homeocareclinicpune
Instagram – https://www.instagram.com/homeocareclinic_in
Website – https://www.homeocareclinic.in
Chat with the best homeopathic doctor privately
If you have any queries regarding your disease or any symptoms, Click to send a WhatsApp message. Our best homeopathy doctor will be happy to answer you.
Book an Appointment
If you want to visit our clinic, Click to book an appointment.
Online treatment
If you are a busy professional, or you are living in a remote town or city, with no best homeopathic doctor near you, Clickhere to start an online homeopathic treatment with the world’s exclusive, most experienced, and best homeopathic clinic, managed by Dr. Vaseem Choudhary world-renowned homeopathic doctor expert!